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Tel: +32 16 58 90 45

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Av. de l'Armée 68 • B-1040 BRUSSELS • BELGIUM

 

GENTAUR FRANCE

Tel: 01 43 25 01 50

9, Rue Lagrange • 75005 PARIS • FRANCE

C-3669 Croton Oil

 
[8001-28-3] M.I. 12: 2665

SPECIAL HAZARD:  TUMOR PROMOTER.  Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure.  WARNING:  Highly irritant to skin and mucous membranes.

Storage:  Store at or below room temperature.  Solubility:  Soluble in DMSO, ethanol, or acetone.  Disposal:  A

 

bulletNatural source of phorbol and phorbol esters.  Formerly used in folk medicine as a counterirritant.  Occasionally used as a standard inflammatory agent in mouse ear testing of anti-inflammatory drugs and drug candidates.
bulletThis is the seed oil of the shrub Croton tiglium Linnaeus.  This seed oil was used in the past as an ingredient in "liniment of croton oil".
bulletPowerful skin irritant and vesicant; violent purgative if ingested.  Avoid all contact with this substance by any route.
bulletNot to be confused with "crotonal", a very different substance whose proper name is crotonaldyhyde.  The term "crotonal" has also been used to mean a solution of crotonaldehyde in kerosene.
bulletFor research use only; not for human use.
 
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