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Tel: +32 16 58 90 45

Fax: + 32 16 50 90 45

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Av. de l'Armée 68 • B-1040 BRUSSELS • BELGIUM

 

GENTAUR FRANCE

Tel: 01 43 25 01 50

9, Rue Lagrange • 75005 PARIS • FRANCE

C-3987 Calyculin A, >98%

 
M.W. 1009.18 C50H81N4 O15 P [101932-71-2]

 

SPECIAL HAZARD:  TUMOR PROMOTER.  Gloves and mask should be worn when using this compound.  Care must be taken to prevent contact through all routes of exposure.

NOTE:  Do not expose to sunlight or fluorescent lights for extended periods.

Storage:  Store at or below -20 ºC.  Solubility:  Soluble in DMSO or ethanol; insoluble in water.  Disposal:  A

 

bulletVery potent inhibitor (Ki = ca. 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase.  Ishihara, H. et al. Biochem. Biophys. Res. Comm. 159: 871-877 (1989).
bulletPotent non-phorbol type tumor promoter.  Suganuma, M. et al. Cancer Res. 50: 3521-3525 (1990).
bulletPlease request Technical Note #19 for additional information.


Calyculin A

 
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