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GENTAUR
Tel: +32 16 58 90 45
Fax: + 32 16 50 90 45
info@genprice.com
Av. de l'Armée 68
• B-1040 BRUSSELS • BELGIUM
GENTAUR FRANCE
Tel: 01 43 25 01 50
9, Rue Lagrange
• 75005 PARIS • FRANCE
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P-2600 PDDHV, >98%
[Phorbol 12,13-didecanoate 20-homovanillate]
Storage: Store at or below -20 ºC. Solubility:
Soluble in DMSO or ethanol. Disposal: A
 | Resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity
for the vanilloid receptor VR-1. Szallasi, A., et al.
"Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity
at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid
receptor VR-1." Br. J. Pharmacol. 128: 428-434 (1999).
Macha, A., et al. "Phorboid 20-homovanillates induce apoptosis
through a VR1-independent mechanism." Chem. Biol. 7: 483-492
(2000). Szallasi, A. and Blumberg, P. M. "Vanilloid (Capsaicin) receptors
and mechanisms." Pharmacol. Rev. 51: 159 (1999). |
| Please inquire for bulk quantities of PDDHV at substantial discounts. |
| Pharmaceutical formulations containing this compound are covered by U.S.
patent 5,643,948, and such formulations and their use in medicine are
covered by European patent EP 0455271, DE P375210808, FR 0455271, GB
0455271, and SW 0455271, all assigned to PKC Pharmaceuticals, Inc., the
parent company of LC Laboratories. |
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