|
GENTAUR
Tel: +32 16 58 90 45
Fax: + 32 16 50 90 45
info@genprice.com
Av. de l'Armée 68
• B-1040 BRUSSELS • BELGIUM
GENTAUR FRANCE
Tel: 01 43 25 01 50
9, Rue Lagrange
• 75005 PARIS • FRANCE
| |
T-5096 Tinyatoxin, >99%
[TNX] [TYX]
| M.W. 598.70 |
C36H38O8
|
[58821-95-7] |
WARNING: Highly irritant to skin and mucous membranes.
Storage: Store at or below -20 ºC. Solubility:
Soluble in DMSO or ethanol. Disposal: A
 | Analog of resiniferatoxin (RTX), Cat. No. R-6712; 6-fold weaker than RTX
in mouse ear erythema tests. |
| Tinyatoxin inhibits specific [3H]RTX binding with a Ki
of 0.8 nM, about three-fold weaker than for resiniferatoxin. Szallasi, A.
and Blumberg, P.M. Brain Res. 547: 335-338 (1991). |
| Please request Technical Note #28 for additional information. |
| Anti-inflammatory uses and pharmaceutical formulations containing this
compound are covered by U.S. patent 5,643,948, and such formulations and
their use in medicine are covered by European patent EP 0455271, DE
P375210808, FR 0455271, GB 0455271 and SW 0455271, all assigned to PKC
Pharmaceuticals, Inc., the parent company of LC Laboratories. |
|
