|
|
|
GENTAUR Tel: +32 16 58 90 45 Fax: + 32 16 50 90 45 Av. de l'Armée 68 • B-1040 BRUSSELS • BELGIUM
GENTAUR FRANCE Tel: 01 43 25 01 50 9, Rue Lagrange • 75005 PARIS • FRANCE |
Anti-Huntington Monoclonal AntibodyMouse Monoclonal (IgG1)
Clone:
H.F5 Immunogen: N-terminal pepetides 1-225 aa. Specificity: Recognize hungtingtin from human and mouse. Formulation: 1mg/ml in PBS, pH 7.4 with 0.05% sodium azide. Frozen liquid. Storage/Stability: Stable for one year at –20ºC from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Aliquot will be stable at 4ºC for 3 months. Application: Western blot and IHC in lipid metabolic research. Huntingtin is a 350kDa protein that is mutated in Huntington's disease (HD). The normal function of Huntingtin still remains uncertain but it has been suggested that it performs a necessary housekeeping function. The abnormal form of Huntingtin aggregates in vitro and forms neuronal intranuclear and cytoplasmic inclusions in HD patients. This antibody detects a 350KD band on western blots but also detects smaller degradation products of Huntingtin in some tissue lysates. |
|
