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GENTAUR
Tel: +32 16 58 90 45
Fax: + 32 16 50 90 45
info@genprice.com
Av. de l'Armée 68
• B-1040 BRUSSELS • BELGIUM
GENTAUR FRANCE
Tel: 01 43 25 01 50
9, Rue Lagrange
• 75005 PARIS • FRANCE
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ISO-NO Activator
| 1. ISO-NO MARK
II Nitric Oxide Meter |
|
ISO-NO Mark II Specifications |
| A/D Converter |
21 bit |
| Display |
2 x 16 digit large LCD |
| Recorder Output |
+ 10 V |
| Recorder Output D/A |
20 bit |
| Recorder Output Resolution |
1 mV/100 pA, 1 mV/10 pA, 1 mV/1 pA |
| Computer Interface |
RS-232 serial port |
| Filter |
5 Hz, 1 Hz, 0.5 Hz, 0.2 Hz, 0.08 Hz (approx.) |
| Calibration and Zero Set |
Auto |
| Dimensions |
11.4 x 8.8 x 3.8 in. (29 x 22.4 x 9.7 cm) |
| Shipping Weight |
10 lb (4.6 kg) |
79-NOMK2
ISO-NO MARK II Nitric Oxide Meter
Includes 2mm shielded sensor and four(4) replacement sleeves |
| 2.
Nitric Oxide(NO) Sensors |
| |
79-ISO-NOPMC |
79-ISO-NOP |
79-ISO-NOP200 |
79-ISO-NOP30 |
79-ISO-NOP007 |
79-ISO-NOPAM |
| Sensor Diameter |
4mm |
2mm |
200 micro |
30 micron |
7 micron |
100 nm |
| Response Time |
< 5 sec |
< 5 sec |
< 5 sec |
< 3 sec |
< 3 sec |
< 3 sec |
Lowest Detection
Limit |
0.3 nM |
1 nM |
1 nM |
1 nM |
0.5 nM |
0.5 nM |
Temperature
Sensitivity |
some |
yes |
yes |
yes |
yes |
some |
| Drift |
none |
none |
< 1pA/Min |
none |
none |
none |
Meter
Resolution |
0.1 PA |
0.1 PA |
0.1 PA |
0.1 PA |
0.1 PA |
0.1 PA |
| Sensitivity |
20 pA/nM |
2 pA/nM |
8 pA/nM |
1.5 pA/nM |
1 pA/nM |
0.5 pA/nM |
Physiological
Interference |
none |
none |
none |
none |
none |
none |
| Application |
Cell culture |
Cell culture,
NO-2, NO-3 |
Cell culture
in vivo |
in vivo |
in vivo
microvessels |
Cellular detection |
| 3.
Nitric Oxide NO Chamber |
Temperature Stabilized closed chamber for measurements of nitric oxide,
oxygen and other species in cell culture
 | Closed chamber design greatly reduces surface area of experimental
solution
exposed to air |
| Matched to WPI’s 2 mm tip diameter ISO NOP and OXEL-1 electrodes, it
fits other
electrodes as well including Kwik-Tip™ ion-selective electrodes and DRIREF-2
and
SDR2 reference electrodes for measurement of Calcium, Potassium, Hydrogen
and
TPP. May be adapted for use with other electrodes as well. |
| Optional use side port for a second electrode permitting simultaneous
measurements
for 2 species, e.g. NO and oxygen |
| Two openings on the Top Port provided for injection of reagents into the
chamber |
| Operating temperature range of 4 - 40 ºC controlled via external
circulating bath |
| Ideal for NO electrode calibration across a range of temperatures |
|
Specifications |
| Volume of sample |
1– 3 mL |
| Compatibility |
| Nitric Oxide Electrode |
| Oxygen Electrode |
| Calcium Electrode KWIKCAL-2 |
| Hydrogen Electrode KWIKH-2 ISO-NOP |
| Potassium Electrode KWIKPOT -2 OXEK-1 |
| TPP (tetraphenylphosphonium) Electrode KWIKTPP-2 |
| Dri-Ref Electrode DRIREF-2 |
| SUPER-Dri-Ref Electrode SDR2 |
|
| Temperature Range |
4—40o C |
| 79-NOCHM |
Nitric Oxide NO Closed Chamber
For use with 2.0mm electrodes |
| 79-NOCHM-P |
Spare Plug Adapter for ISO-NOP
Nitric Oxide Electrode |
| D. 2-CHANNEL
RECORDING SYTEM FOR DATA AQUISITION |
| The perfect accessory for analytical chemistry applications such as
WPI’s nitric oxide
sensing system, EVOMX, pH Electrodes, Ion Selective Electrodes and the ISO2
meter |
| This PC-based 2-channel data acquisition system is a multifunctional
meter and chart
recorder |
| The Duo•18 provides both economical hardware and user-friendly software
for laboratory
research and industry applications requiring long on-line recording and data
processing
times for voltage or current signals, such as nitric oxide, carbon dioxide,
oxygen (ppm, %),
pH, pK, pCa, pTPP, Ohms, temperature, pressure and light. |
| Hardware Features |
Software Features
|
| 18-bit A/D converter (1 part in 262,144) |
| Analog input: 2 channels BNC Single ended |
| Selectable low noise gains: 1x, 10x, 100x |
| Input voltage range: +/- 5 V, +/- 0.5 V, +/-
0.05V |
| Input A/D resolution: 22μV, 2.2 μV, 0.22 μV,
(1 LSB) |
| Input impedance: 1012 Ohms |
| Sampling speed: 5 samples/sec (independent
per channel) |
| RS-232 interface 9pin and 25 pin connectors
supplied |
| 12-volt DC power |
Separate external reference ground pins for pH probes
|
| On screen chart recorder and digital panel meter |
| Channel independent auto-zeroing and sloping. |
| Data saving, loading, printing |
| Automatic export of text file, readable by any application |
| Data editing -- cut, copy, clear, paste within the plot. |
| Click and look calculation of acquired data -- value,
delta, averaging, integral, minimum., maximum; while
you record. |
| Expandable vertical and horizontal scales convertible to
different units of measurements and slopes. |
| Software controlled recording time up to months. |
| Automatic indexing of file number for uninterrupted and
continuous recording. |
|
| 79-DUO18 |
Duo-18 Data Recording System
System Requirements
• Windows, 98, 2000, Me or Windows NT
• IBM -compatible Pentiumr® (minimum), 16 Meg RAM, COM port 1-4 |
| E. GSNO
S-Nitrosoglutathione (C10H16N4)7S) |
GSNO is a useful NO donor which slowly and spontaneously releases NO under
physiological conditions.
GSNO has been identified in vivo as a potential storage and transport vehicle
for NO in the body. It
selectively inhibits platelet inactivation 1 ,NF-• B activation 2,3 ,and
endothelial cell proliferation 4 and
displays cardioprotective effects 5 .It has also been shown to induce apoptosis
in T cells 6 .
| 79-GSNO-50 |
50 mG vial |
| 79-GSNO-100 |
100 mG vial |
| 79-GSNO-500 |
500 mG vial |
| F. NITRALIZER™
Nitrate Reductor |
Reagentless microreactor converts nitrate to nitrite at room temperature in
minutes.
| Reduction of nitrate to nitrite at room temperature. |
| No need to add any reagent--just buffer your sample. |
| 100% conversion effeciency typically in less than five minutes! * |
| Disposable reactor vials can be used for many samples. |
| Only a few microliters of sample needed. |
| No extra equipment needed -- it's portable. |
|
79-NITRALIZER |
Nitrate Reductor, 1.5 mL capacity (5 reactors, 100
vials) |
After an ISO-NOP 2 mm sensor is used for long periods, sensitivity may become
reduced and
response time may increase. This little device can restore sensor performance to
original levels.
Simply immerse sensor (without sleeve) and reference electrode (RC1T, included)
in an activating
solution, then connect them to the ISO-NOP Rejuvenator. Pressing the button
applies an
electric waveform for a few seconds. 9v alkaline battery included.
| 79-JUV |
ISO-NOP Rejuvenator |
Pre-Polarizer for NO Sensors
To achieve a stable background current value, electrochemical sensors need
to
be left under the applied potential (amperometric measurement) for some time
to allow the current to decay. This is not very he lpful for the investigator
who is
planing on using more than one sensor, or if a sensor is damaged during an
experiment.
The new ISO-NO Activator solves this problem. This small batterypowered
device applies potential to the electrode equivalent to the potential applied
by the meter. Consequently, a sensor which has been connected to the activator
may be transferred to the meter and used immediately for measurements.
Keep extra NO sensors ready to use
| 79-NSA-1 |
ISO-NO Activator for one sensor |
| 79-NSA-2 |
ISO-NO Activator for two sensors |
| 79-NSA-3 |
ISO-NO Activator for three sensors |
| I. SNAP
(S-Nitroso-N-acetyl-D,L-penicillamine) |
SNAP is a stable green crystalline S-nitrosothiol compound that mimics the
action of nitric oxide in vivo. It has vasodilatory
properties and has been shown to relax isolated bovine coronary artery rings by
activating soluble granulate cyclase. This reagent
also actuates apoptosis in mouse thymocytes and has been accounted for
reversible inactivation of protein Kinase C. SNAP can
be used for calibration of all WPI NO sensors.
| 79-SNAP50 |
SNAP, 50 mg vial |
| 79-SNAP100 |
SNAP, 100 mg vial |
| 79-SNAP500 |
SNAP, 500 mg vial |
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