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Tel: +32 16 58 90 45

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Av. de l'Armée 68 • B-1040 BRUSSELS • BELGIUM

 

GENTAUR FRANCE

Tel: 01 43 25 01 50

9, Rue Lagrange • 75005 PARIS • FRANCE

ZytoDot - Products for CISH analysis
 

Safe and simple detection of genomic alterations using light microscopy!

ZytoVision offers an expanding range of ZytoDot products for the detection of aneuploidies and gene amplifications, e.g. of HER2, by Chromogenic in situ Hybridization (CISH) using light microscopy.

 

Overview
ZytoDot probes can be used on various sample types in all aspects of routine and research work in genetics and oncology/pathology. The ZytoDot system uses tagged DNA probes which are indirectly detected using an enzyme-conjugated antibody targeting the tags. The enzymatic reaction of the chromogenic substrate DAB leads to the formation of strong permanent brown signals that can be visualized by light microscopy at 40x. Thus, the ZytoDot System allows the simultaneous observation of gene amplification and tissue morphology.

 

CISH analysis of paraffin embedded tissues using the ZytoDot SPEC HER2 Probe (C-3001). No HER2 gene amplification (left); HER2 amplification >10 dots (middle); HER2 amplification with clusters and dots (right).


Product Info
The ZytoDot product line comprises CEN probes specific for highly repeated satellite sequences located at the centromeric regions of human chromosomes, as well as Digoxigenin-labelled SPEC probes specific for single copy DNA sequences.
Advanced specificity and less background of the single copy SPEC probes is obtained by the unique ZytoVision® Repeat Subtraction Technique.

 

Prod. No. Product Price €

Pack Size


ZytoDot in situ hybridization Probes
 
C-3001 ZytoDot SPEC HER2 Probe 562 25 Assays
C-3004 ZytoDot SPEC EGFR Probe 562 25 Assays
C-3008 ZytoDot CEN 7 Probe  coming soon 25 Assays
C-3002CE ZytoDot CEN 6 Probe 315 25 Assays
C-3008CE ZytoDot CEN 7 Probe 315 25 Assays
C-3013 ZytoDot SPEC CMYC Probe 375 25 Assays
C-3015CE ZytoDot DAB solution A and B 122 10 ml
C-3014CE ZytoDot CEN 12 Probe 315 25 Assays
C-3006 ZytoDot CEN 17 Probe   inquire 25 Assays

ZytoDot in situ hybridization Kits
 
C-3003 ZytoDot HER2 SPEC Probe Kit  inquire 20 Assays
C-3009 ZytoDot EGFR SPEC Probe Kit  coming soon 20 Assays
C-3005 ZytoDot CISH Polymer Detection Kit  inquire  
C-3010 ZytoDot Wash Buffer Set inquire  


For more information concerning currently available ZytoDot products please click here.

 
  info@genprice.com
GENTAUR EUROPE Tel: +32 16 58 90 45 Fax: +32 16 58 90 45 Av. de l'Armée 68 • B-1040 BRUSSELS • BELGIUM
GENTAUR FRANCE Tel: 01 43 25 01 50 Fax: 01 43 25 01 60 9, Rue Lagrange • 75005 PARIS • FRANCE
GENTAUR ITALY Tel: 02 36 00 65 93 Fax: 02 36 00 65 94 20135 MILANO • ITALY
GENTAUR GERMANY Tel: +32 16 58 90 45 Fax: +32 16 58 90 45  
JAPAN Tel: +81 78 386 2860 Fax: +81 78 306 0296

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